Injectables · Skin Quality

Bio-Remodelling Injectable
(Profhilo®)

A doctor-administered hyaluronic acid bio-remodeller — commonly known by the brand Profhilo® — that delivers intense hydration and stimulates collagen and elastin within the skin. Improves overall skin quality rather than adding volume.

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Soft clinical atmosphere — bio-remodelling injectable treatment environment at IVI Medical Clinic

What is bio-remodelling injection?

Bio-remodelling injection is a category of injectable treatment that uses a stabilised, high-concentration form of pure hyaluronic acid (HA). Unlike traditional dermal fillers, it is not designed to add volume or fill lines — instead, the product disperses beneath the skin to support tissue remodelling and hydration. At IVI, this service is delivered using a registered bio-remodelling product (Profhilo®), administered by an MOH-licensed doctor.

The product uses a thermally-bonded form of HA that has been shown in clinical studies to support collagen and elastin processes within the skin — contributing to improvements in skin tone, texture, and elasticity over a course of treatments.

What does bio-remodelling injection address?

  • Loss of skin hydration and a dull, tired appearance
  • Skin laxity and loss of firmness in the face, neck, and hands
  • Fine lines and crepey skin texture
  • Overall skin quality improvement and radiance

The Procedure

The product is injected using the patented Bio Aesthetic Points (BAP) technique — five specific injection points on each side of the face that maximise the spread of the HA through the skin tissue. The treatment takes approximately 15–20 minutes with minimal discomfort.

The standard protocol consists of 2 sessions, spaced 4 weeks apart. Most patients see initial results within 2 weeks of the first session, with full results visible at 4 weeks after the second session.

What results can I expect?

After a full course of treatment, patients typically experience significantly improved skin hydration, a noticeable glow, firmer skin texture, and a reduction in fine lines. Many patients report that friends and family ask if they've "been on holiday" or "had a good night's sleep."

Results typically last 6 months. We recommend a maintenance session every 6 months to sustain the effects.

Is this treatment suitable for me?

Bio-remodelling injection is suitable for most adults looking to improve overall skin quality. It is particularly effective for patients in their 30s–50s experiencing the first signs of ageing — loss of radiance, early laxity, and dehydration — and for those who want a natural, no-downtime skin improvement.

Frequently Asked Questions

Is the treatment painful? +
The injections are generally well-tolerated. A topical numbing cream is applied before treatment. The Bio Aesthetic Points (BAP) technique uses fine needles for minimal discomfort. Most patients describe a slight pinch sensation.
How many sessions do I need? +
The standard protocol is 2 sessions, 4 weeks apart. Maintenance sessions every 6 months are recommended to sustain results. Some patients choose to do 3 sessions for more significant concerns.
Is there any downtime? +
Bio-remodelling injections have minimal downtime. You may experience slight redness, swelling, or small bumps at the injection sites for 24–48 hours. You can return to normal activities the same day.
Can this be combined with other treatments? +
Yes — bio-remodelling injection is commonly combined with other treatments such as neurotoxin injection, dermal fillers, polynucleotide skin rejuvenation, and pigmentation laser. Suitability and combination is assessed by your doctor.
Considering this treatment?
Book a structured skin assessment with one of our MOH-licensed doctors. We’ll discuss whether this protocol is right for your skin and explain realistic outcomes for your specific concern.

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Book a consultation at our Orchard or Tampines clinic.